I had to go off of tagrisso for a month due to a knee replacement surgery. My next pet scan they found a spot on my lung. They said it was too small yet to biopsy so they would see if it increased in size by the next PET scan. I went back on to tagrisso after a month as the surgeon suggested and on my next PET scan the spot on my lung was gone. As of February 2025 I will have been on tagrisso three years and my oncologist said that it is suggested by the FDA that people discontinue after three years. Because of the fact that I went off of it and they found a spot, it scares me to stop tagrisso.st I can't find anything about why on the Internet. Does anyone know why?